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Beilstein J. Org. Chem. 2017, 13, 127–137, doi:10.3762/bjoc.13.16
Graphical Abstract
Scheme 1: 2’-Propargylated nucleosides as “clickable” DNA/RNA building blocks with ribo (1) and arabino (2) c...
Scheme 2: Synthesis of phosphoramidite 7 and modified DNA. a) TIPDSiCl2, pyridine, 2 h at 0 °C, 16 h at rt, 8...
Scheme 3: Structures of donor dyes D1–D4 as modifications of DNA2a and DNA2r and structures of acceptor dyes ...
Figure 1: Representative demonstration of the fluorescence readout differences between the four arabino/ribo ...
Figure 2: Confocal microscopy of HeLa cells after transfection with DNA2aD1–DNA3rD5 (row 1), DNA2rD1–DNA3aD8 ...